Condition
Acute Kidney Injury
Almost entirely preclinical evidence.
Quick summary
- • Human data is minimal
Overview
Acute kidney injury is an emergency requiring standard care.
Mechanisms studied
Studied mainly in animal models.
Human research
No human conclusions yet.
Safety
Reported adverse events are mostly local — swelling, pain, or bruising at the harvest and injection sites. Infection and cell-processing quality remain the key risks to monitor.
Evidence limitations
Existing studies are limited by sample size, methodology, and follow-up, and SVF preparation differs substantially between centres, making cross-study comparison difficult.
Latest PubMed research
172 indexed studies for this condition · auto-updated 17 August 2026
- Level ASystematic ReviewEurope PMC
Worldwide hotspots and trends in stem cell therapy for kidney disease in the last decade: a bibliometric and visualization analysis from 2015 to 2024
Systematic Review on Chronic Kidney Disease, Acute Kidney Injury, published in Front Immunol (2025) — summary generated from the PubMed abstract.
- 2025
Front Immunol2 citations - Level AMeta-analysisEurope PMC
Protective role of exosomes in renal ischemia-reperfusion injury: a systematic review and meta-analysis
Meta-analysis on Chronic Kidney Disease, Acute Kidney Injury, published in Front Pharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Front Pharmacol1 citations - Level AMeta-analysisEurope PMC
Extracellular vesicles for ischemia/reperfusion injury-induced acute kidney injury: a systematic review and meta-analysis of data from animal models
Meta-analysis on Acute Kidney Injury, published in Syst Rev (2022) — summary generated from the PubMed abstract.
- 2022
Syst Rev8 citations - Level AMeta-analysisEurope PMC
Extracellular vesicles for acute kidney injury in preclinical rodent models: a meta-analysis
Meta-analysis with a reported sample of 552 on Acute Kidney Injury, Chronic Inflammation, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
- n = 552
Stem Cell Res Ther35 citations - Level AMeta-analysisPubMed
Concise Review: Using Fat to Fight Disease: A Systematic Review of Nonhomologous Adipose-Derived Stromal/Stem Cell Therapies.
Meta-analysis on Osteoarthritis, Acute Kidney Injury, Cardiovascular Disease, Stroke Research, published in Stem Cells (2018) — summary generated from the PubMed abstract.
- 2018
Stem Cells101 citations - Level AMeta-analysisEurope PMC
Extracellular vesicles derived from mesenchymal stromal cells may possess increased therapeutic potential for acute kidney injury compared with conditioned medium in rodent models: A meta-analysis
Meta-analysis on Chronic Kidney Disease, Acute Kidney Injury, published in Exp Ther Med (2016) — summary generated from the PubMed abstract.
- 2016
Exp Ther Med17 citations
Last updated: 2026-06-18 · arisa-w