AB046. Potential application of adipose derived stem cells for urological disease
Laboratory Study, published in Transl Androl Urol (2015) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- Transl Androl Urol (2015)
- Reported sample size
- —
- Source database
- Europe PMC
- PMCID
- PMC4708719
Abstract (original English)
Adipose derived stem cells (ADSCs) are a somatic stem cell population contained in fat tissue that may benefit the recovery of urological disease by using a stem cell based therapy. ADSCs have previously been shown to possess stem cell properties such as transdifferentiation and self-renewal, which are a somatic stem cell population contained in fat tissue. ADSCs share the same properties of all stem cells, such as the ability to divide and renew themselves for long periods, and differentiate into specialized cells. Similar to other kinds of MSC, ADSC express multiple CD marker antigens (CD73+ CD90+ CD105+ CD34+/- CD11b- CD104b- CD19- CD31- CD45- SMA-). Meanwhile, the ADSCs have many advantages, including the ability to isolate many more stem cells using a minimally invasive surgical procedure for extraction of the adipose tissue. Available evidence concerning adipose derived stem cell availability, differentiation into functional cells, and the potential of these cells were examined the current data (from 1964 to 2014) associated with the definition, characterization, differentiation, and application of adipose derived stem cells for the cell-based therapies of urological diseases. The adipose-derived stem cells are regarded as candidates for the treatment of urological diseases due to many factors. These stem cells can easily be obtained in large quantities and possess the po
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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