AB190. The experimental study of in vitro differentiation of human adipose derived stem cells into hematopoietic progenitor cells
Laboratory Study, published in Transl Androl Urol (2014) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- Transl Androl Urol (2014)
- Reported sample size
- —
- Source database
- Europe PMC
- PMCID
- PMC4708408
Abstract (original English)
Objective To explore the in vitro culture method of inducing human adipose derived stem cells (ADSCs) differentiation into hematopoietic progenitor cells (HPCs). Methods Using special modified serum-free medium for in vitro induction of ADSCs differentiation into HPCs, and using fluorescence activated cell sorter (FACS), reverse transcription polymerase chain reaction (RT-PCR) and morphological observation methods for preliminary identification of the biological characteristics of induced ADSCs cells. Results: The expression levels of positive markers of HPCs concluding CD34, CD45, KDR and CD105 are significantly higher in induced ADSCs group than that in uninduced ADSCs group, and ADSCs formed sphere clusters from adherent cells after induction. Conclusions: The experimental procedures of in vitro culture method can preliminary induce ADSCs differentiation into HPCs using the special modified serum-free medium.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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