Abstraits AUQ 2013

Early human evidence such as case series or small samples is exploring possible benefits.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Introduction and objectives : Local tumour destruction (LTD) is a recommended therapy alternative for localized T1 renal cell carcinoma (RCC) for patients unfit for surgery. We examined patterns of use and complication rates of LTD in a large population-based cohort. Methods : Overall, 5285 patients undergoing LTD for RCC were extracted from the Nationwide Inpatient Sample database from 2006 to 2010. We assessed patient and hospital characteristics, as well as postoperative complications using International Classification of Diseases, 9th Revision codes. The impact of patient and hospital characteristics on peri-interventional complications (overall or specific) was tested using univariable or multivariable logistic regression models. Results : Most patients were male (61.2%), aged 70 years or older (50.3%) and most had two or more comorbidities (57.1%). Most LTDs were performed at urban (93.5%), teaching (57.7%) and low-volume (75.7%) hospitals. Overall complications were recorded in 15.4%. In multivariable analyses adjusted for clustering, overall complications occurred more frequently in older, sicker patients who were treated at low-volume hospitals (all p Conclusions : LTD is recommended in older and sicker individuals. These recommendations are reflected in LTD use patterns recorded in the current study. Complications of LTD occur in one out of six patients and are more f

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.