Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

Adipocytes at the Core of Bone Function.

Grandl G., Wolfrum C.

Laboratory Study, published in Cell Stem Cell (2017) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Cell Stem Cell (2017)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
28575686
DOI
10.1016/j.stem.2017.05.008

Abstract (original English)

Marrow adipose tissue (MAT) is a specialized adipose tissue with endocrine function found in bone marrow. In this issue of Cell Stem Cell, Ambrosi et al. (2017) identify a stem cell population in the bone marrow that can give rise to both osteogenic and adipogenic MAT precursors and is regulated by diet and aging and affects bone functionality.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AdipocytesAdipose TissueBone MarrowBone RegenerationHematopoietic Stem Cell TransplantationHumansObesity

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