Level D· Scientific groundwork from lab and animal studiesAnimal StudyEurope PMC

Adipose Tissue: Sanctuary for HIV/SIV Persistence and Replication

Pallikkuth S., Mohan M.

Animal Study, published in Trends Microbiol (2015) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Trends Microbiol (2015)
Reported sample size
—
Source database
Europe PMC
PMID
26588868
PMCID
PMC4679589
DOI
10.1016/j.tim.2015.11.001
Citations
9

Abstract (original English)

This commentary highlights new findings from a recent study identifying adipose tissue as a potential HIV reservoir and a major site of inflammation during chronic human/simian immunodeficiency virus (HIV/SIV) infection. A concise discussion about upcoming challenges and new research avenues for reducing chronic adipose inflammation during HIV/SIV infection is presented.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesMacrophagesAnimalsMacaca mulattaHumansHIVHIV InfectionsSimian Acquired Immunodeficiency Syndrome

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