[Advances in the regulation of functions of hepatic stellate cells by exosomes]
Ye QN., Ping J., Xu LM.
Narrative Review, published in Zhonghua Gan Zang Bing Za Zhi (2020) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Zhonghua Gan Zang Bing Za Zhi (2020)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 33256289
- PMCID
- PMC12769878
- DOI
- 10.3760/cma.j.cn501113-20190412-00123
- Citations
- 1
Abstract (original English)
Exosomes are small vesicles with a bilayer membrane structure secreted by a variety of cells. They are widely distributed in a variety of body fluids and contain proteins, nucleic acids and other components. They can mediate information transmission between cells and participate in a variety of physiological and pathological activities of cells. Hepatocytes, hepatic sinus endothelial cells and other cells were able to communicate with hepatic stellate cells via exosomes, and regulate the activation, migration, apoptosis and other biological activities of hepatic stellate cells. In this review, the recent advances in the regulation of exosomes on the biological activity of hepatic stellate cells were reviewed.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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