From Aesthetic to Alarming: Ductal Carcinoma In Situ Following Breast Fat Grafting
Ashkar L., Abufarea BM., Alkaeid FF., Alruwaithi RO., Nadhra RW.
Case Report / Series, published in Cureus (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Case Report / Series
- Journal
- Cureus (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40656298
- PMCID
- PMC12256079
- DOI
- 10.7759/cureus.85934
- Citations
- 1
Abstract (original English)
This case presents a rare occurrence of ductal carcinoma in situ (DCIS) in a patient with a history of bilateral iatrogenic fat injections, aiming to contribute to the ongoing discussion on potential associations between fat grafting and breast pathology. A 43-year-old Saudi woman presented with bilateral palpable masses at the sites of previous fat grafting performed two years earlier. Despite having no significant risk factors or family history of breast cancer, imaging revealed a suspicious asymmetry adjacent to the palpable area in the left breast. Biopsy of this region confirmed fat necrosis with foci of atypical ductal hyperplasia and low-grade DCIS. This case underscores the importance of vigilant follow-up in patients undergoing autologous fat grafting to the breast.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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