Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

Aneuploidy of stem cells isolated from human adipose tissue.

Bochkov NP., Nikitina VA., Buyanovskaya OA., Voronina ES., Goldstein DV., Kuleshov NP.

Laboratory Study, published in Bull Exp Biol Med (2008) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Bull Exp Biol Med (2008)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
19240856
DOI
10.1007/s10517-008-0293-1

Abstract (original English)

The incidence of autosomes 6 and 8 aneuploidy in stem cell cultures derived from adipose tissue was evaluated at different stages of culturing. Monosomy was more incident than trisomy during the early passages. Distribution of cultures by the incidence of aneuploidy in different chromosomes was virtually the same. Clones with chromosome 6 monosomy were detected in two cultures during late passages.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueAneuploidyCells, CulturedChromosomes, Human, Pair 6Chromosomes, Human, Pair 8HumansIn Situ Hybridization, FluorescenceKaryotypingStem Cells

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