Level D· Scientific groundwork from lab and animal studiesLaboratory StudyEurope PMCOpen access

Applications and challenges of 3D printing in female reproductive system research

Setareyi R., Khoshandam A., Kianirad S., Saadatmand M., Naji M.

Laboratory Study, published in 3D Print Med (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
3D Print Med (2025)
Reported sample size
—
Source database
Europe PMC
PMID
41188677
PMCID
PMC12587555
DOI
10.1186/s41205-025-00302-w

Abstract (original English)

The optimal functioning of the female reproductive system is crucial for human health, since failure frequently results in significant repercussions for fertility, sexual health, and general quality of life. These organs function through a meticulously coordinated and precisely regulated mechanism to facilitate oocyte production and embryonic development. Recently, 3D printing has become a formidable approach for producing intricate, biomimetic objects with exceptional spatial accuracy. Substantial attempts were undertaken to integrate living cells and bioactive chemicals into printed constructions for biomedical purposes. This review presents a thorough investigation of works employing 3D printing within the realm of the female reproductive system. We classified these studies based on their principal applications-tissue engineering, drug delivery, and disease modeling-and described essential data about printing methodologies, bioinks, cell types, animal models, integrated bioactive compounds, and outcomes.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence

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