Level C· Early human research exploring benefitsCase Report / SeriesPubMed

Arthroscopic debridement with microfragmented adipose tissue for wrist and hand chondral lesions in professional athletes.

Raggini F., Lombardo MDM., Salini V., Pegoli L.

Case Report / Series with a reported sample of 5 on Cartilage Damage, published in Hand Surg Rehabil (2026) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Case Report / Series
Journal
Hand Surg Rehabil (2026)
Country
France
Reported sample size
5
Source database
PubMed
PMID
41802654
DOI
10.1016/j.hansur.2026.102636

Abstract (original English)

Background Focal chondral lesions of the wrist and hand are an underrecognized source of pain and functional limitation in athletes. Their management remains challenging due to the limited healing capacity of hyaline cartilage, the biomechanical demands of small joints, and the lack of standardized treatment algorithms. Arthroscopy allows accurate diagnosis and targeted treatment with minimal morbidity, while biologic augmentation using autologous adipose-derived products has emerged as a potential adjunct to improve clinical outcomes. Objective To evaluate the clinical outcomes of arthroscopic debridement combined with intra- and peri-articular injection of autologous microfragmented adipose tissue in professional athletes affected by focal chondral lesions of the wrist and hand. Patients and methods This prospective single-center case series included six professional athletes (5 men, 1 woman; mean age 26.3 years) treated between June 2020 and April 2022. A total of nine joints were addressed (3 radiocarpal and 6 metacarpophalangeal). All patients underwent standardized wrist or hand arthroscopy followed by intra- and peri-articular injection of autologous microfragmented adipose tissue processed using a closed mechanical system. Chondral lesions were graded according to the International Cartilage Repair Society classification. Clinical outcomes included pain (visual analog s

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
HumansDebridementArthroscopyAdipose TissueAdultFemaleProspective StudiesMaleCartilage, ArticularYoung Adult

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