Attitudes and Knowledge Regarding Adipose-Derived Stem Cell Therapy: A Survey of Canadian Orthopedic Surgeons.
Liu HZ., Khanna V., Ayeni OR., Parasu N.
Laboratory Study, published in Cureus (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- Cureus (2025)
- Country
- United States
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 40693051
- PMCID
- PMC12277920
- DOI
- 10.7759/cureus.86456
Abstract (original English)
Background Adipose-derived stem cells (ADSCs) hold therapeutic potential for the treatment of orthopedic conditions. However, no surveys to date have evaluated physicians' awareness and receptiveness toward these therapies - an essential step in assessing the Canadian healthcare system's readiness for ADSC implementation, alongside regulatory and technical considerations. We hypothesized a generally low level of exposure to this therapeutic modality, with higher levels of awareness and interest expected among respondents specializing in sports medicine and reconstruction. Methods An eight-item questionnaire was distributed to members of the Arthroscopic Association of Canada and the Orthopedic Division at (redacted for blinding) University. Statistical analysis was conducted using mixed-effects logistic regression. Results The survey achieved a 12.9% response rate, yielding 50 responses. Most respondents (62%) reported hearing about ADSCs only a few times per year, primarily through scientific journals and colleagues. Only 10% expressed interest in incorporating ADSCs into their future practice. Common barriers included insufficient evidence, high costs, and regulatory limitations. No significant association was found between orthopedic subspecialty and receptiveness to ADSC therapy. Conclusions Canadian orthopedic surgeons show limited awareness of, and willingness to adopt, A
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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