Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Autologous Fat Grafting Restores Soft-tissue Contour Deformities after Vascular Anomaly Surgery

Teresa Minjung O., Chan K., Brennan T., Roden D., Shamouelian D., Chung HY.

Retrospective Study with a reported sample of 27 on Scar, published in Plast Reconstr Surg Glob Open (2019) — summary generated from the PubMed abstract.

Open my reading list
Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Plast Reconstr Surg Glob Open (2019)
Reported sample size
27
Source database
Europe PMC
PMID
31333935
PMCID
PMC6571319
DOI
10.1097/gox.0000000000002196
Citations
5

Abstract (original English)

Background Soft-tissue loss is expected after resection of large vascular lesions. Autologous fat transfer improves asymmetries; however, systematic outcomes are not previously described for vascular anomaly reconstruction. Methods Retrospective chart review from 2012 to 2015 included patients receiving autologous fat transfers for soft-tissue defects during or following vascular anomaly surgery at a tertiary care center. Patients received dermal en bloc fat grafts, lipoaspirates, or both. Pre- and postoperative photographs were blindly reviewed by 3 facial plastic surgeons using a 5-point scale. Dermal abdominal en bloc fat grafts were placed immediately after excision of a vascular anomaly. Lipoaspirate fat grafting was performed using liposuction (modified Coleman technique) and centrifugation. The effectiveness of fat transfers was assessed using patients' photographs. Final follow-up was 6 months to 5 years. Results There were 35 autologous fat transfer surgeries in 27 patients. Fourteen patients received en bloc dermal fat grafts (14 total), 13 lipoaspirate transfers (21 total), and 3 both. Ages ranged from 2 to 69 years (mean = 25 years). Majority of patients (81%) had head and neck lesions. Average volume of fat injected was 16.5 mL (range 0.8-100 mL). The average observer rating score was 2.45 [1-5 (5-point scale)] in the en bloc fat graft group versus 3.83 in the lipo

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.

Related research