Autologous Fat Grafting Restores Soft-tissue Contour Deformities after Vascular Anomaly Surgery
Teresa Minjung O., Chan K., Brennan T., Roden D., Shamouelian D., Chung HY.
Retrospective Study with a reported sample of 27 on Scar, published in Plast Reconstr Surg Glob Open (2019) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Retrospective Study
- Journal
- Plast Reconstr Surg Glob Open (2019)
- Reported sample size
- 27
- Source database
- Europe PMC
- PMID
- 31333935
- PMCID
- PMC6571319
- DOI
- 10.1097/gox.0000000000002196
- Citations
- 5
Abstract (original English)
Background Soft-tissue loss is expected after resection of large vascular lesions. Autologous fat transfer improves asymmetries; however, systematic outcomes are not previously described for vascular anomaly reconstruction. Methods Retrospective chart review from 2012 to 2015 included patients receiving autologous fat transfers for soft-tissue defects during or following vascular anomaly surgery at a tertiary care center. Patients received dermal en bloc fat grafts, lipoaspirates, or both. Pre- and postoperative photographs were blindly reviewed by 3 facial plastic surgeons using a 5-point scale. Dermal abdominal en bloc fat grafts were placed immediately after excision of a vascular anomaly. Lipoaspirate fat grafting was performed using liposuction (modified Coleman technique) and centrifugation. The effectiveness of fat transfers was assessed using patients' photographs. Final follow-up was 6 months to 5 years. Results There were 35 autologous fat transfer surgeries in 27 patients. Fourteen patients received en bloc dermal fat grafts (14 total), 13 lipoaspirate transfers (21 total), and 3 both. Ages ranged from 2 to 69 years (mean = 25 years). Majority of patients (81%) had head and neck lesions. Average volume of fat injected was 16.5 mL (range 0.8-100 mL). The average observer rating score was 2.45 [1-5 (5-point scale)] in the en bloc fat graft group versus 3.83 in the lipo
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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