Autologous Fat Grafting for Third-Degree Hand Burns: A Case Report With Patient and Observer Scar Assessment (POSAS)-Based Evaluation.

Early human evidence such as case series or small samples is exploring possible benefits.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Wound management remains a fundamental component of plastic and reconstructive surgery [1]. Among the available treatment options, autologous fat grafting has gained attention due to its ability to support soft-tissue regeneration, enhance revascularization, and modulate immune responses through the secretion of bioactive molecules, cytokines, and growth factors [2]. It also provides anti-inflammatory, proangiogenic, and regenerative effects, which are particularly valuable in treating conditions affecting the hand and upper extremity [1,3]. Human adipose tissue represents a highly suitable implantable biomaterial owing to its rich reservoir of bioactive substances, such as extracellular matrix constituents, diverse growth factors, and stem or progenitor cell populations [2]. The present case illustrates how the use of autologous fat grafts as a biological dressing in a patient with a third-degree thermal burn and extensor tendon exposure in the hand resulted in favorable wound bed evolution and effective preparation for subsequent skin grafting. We present the case of a 47-year-old female patient with a 25 cm² soft-tissue defect on the dorsum of the left hand secondary to a third-degree thermal burn caused by contact with a metal sheet, with tendon exposure of the extensor mechanism of two fingers. The defect was managed using decanted autologous fat grafts, without centrifuga

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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