Autologous Fat Grafting Versus Alloplastic Materials in Post-Traumatic Urogenital Reconstruction
Gilani F., Rizwan M., Haq I., Umar Z., Farooq MM., Aziz U.
Prospective Study with a reported sample of 204, published in Cureus (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- Cureus (2025)
- Reported sample size
- 204
- Source database
- Europe PMC
- PMID
- 41267716
- PMCID
- PMC12629139
- DOI
- 10.7759/cureus.94992
Abstract (original English)
Background Traumatic soft tissue injuries to the urogenital area need reconstructive procedures that minimize complications while restoring both shape and function. Objective To compare the reconstructive outcomes of autologous fat grafting versus alloplastic materials in the repair of post-traumatic urogenital soft tissue defects with respect to complication rates, aesthetic outcomes, and patient-reported satisfaction in a collaborative plastic surgery-urology clinical setting. Methodology This was a descriptive, multicenter observational study conducted from November 2022 to October 2024 at Shifa International Hospitals, Islamabad, along with Khyber Teaching Hospital, Peshawar, and Hayatabad Medical Complex, Peshawar. Out of 204 patients with post-traumatic urogenital abnormalities who were at least 18 years old, 106 had autologous fat grafting, and 98 had alloplastic repair. At six and 12 months, prospective data were gathered on demographics, injury features, surgical parameters, postoperative complications, cosmetic results (as judged by a panel of blinded people), and patient satisfaction (5-point Likert scale). IBM Corp. Released 2020. IBM SPSS Statistics for Windows, Version 26. Armonk, NY: IBM Corp. was used for statistical analysis, which includes chi-square, t-tests, and multivariable regression. Results Mean surgical time was shorter in the fat grafting group (92.4
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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