Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMedOpen access

Autologous Microfragmented Adipose Tissue Injection Combined With Core Decompression for Treatment of Early-Stage Osteonecrosis of the Femoral Head.

Deng Z., Zhu X., Su J., Zhang L., Zhang C., Yang S.

Laboratory Study on Chronic Inflammation, published in Arthrosc Tech (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Arthrosc Tech (2025)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
40656747
PMCID
PMC12255460
DOI
10.1016/j.eats.2025.103548

Abstract (original English)

Osteonecrosis of the femoral head is a disease that occurs frequently in the young and middle-aged population. Because of its high disability rate, it affects the ability to work, so early treatment of this disease is particularly important. Microfragmented adipose tissue contains high levels of adipose-derived stem cells, which show osteoprotective and anti-inflammatory qualities. This Technical Note aims to introduce in detail the harvesting and lipogems processing of autologous microfragmented adipose tissue, combined with core decompression surgery in treating early-stage osteonecrosis of the femoral head.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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