[Autologous nanofat transplantation for scar treatment].
von Arenstorff JF., Gravergaard AE., Bille C.
Randomized Controlled Trial on Scar, published in Ugeskr Laeger (2022) — summary generated from the PubMed abstract.
Several human studies show positive signals, while research methods and sample sizes continue to develop.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Randomized Controlled Trial
- Journal
- Ugeskr Laeger (2022)
- Country
- Denmark
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 35315762
Abstract (original English)
Damaging the normal skin barrier results in a cascade of reactions resulting in scar formation. Transforming growth factors cause the proliferation of fibroblasts to myofibroblasts, which keep secreting collagen. There are indications, that the proliferation might be inhibited by adipose-derived stem cells (ADSC). Nanofat is a liquid substance containing ADSC. This review is based on five observational human studies, where nanofat was injected into a variant of scars. A significant improvement was demonstrated in all the studies. Scars treated within five years has a better chance of regeneration. Randomized controlled trials are warranted.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Several human studies show positive signals, while research methods and sample sizes continue to develop.
How we grade evidenceBrowse all related research
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