Barraquer Simons Syndrome: Case Series and Review of Surgical Treatments for Facial Lipodystrophy

Early human evidence such as case series or small samples is exploring possible benefits.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Background Barraquer Simons Syndrome (BSS) is a subtype of idiopathic acquired lipodystrophy, wherein patients-mostly female-lose subcutaneous fat in the upper half of the body starting in childhood or puberty. A disproportionate fat allocation can be seen in the trochanteric region and thighs. Methods Along with three cases of lipoatrophy treated at our hospital, we conducted a comprehensive review and presented the treatments in the literature for improving bilateral facial lipodystrophy. Results Flaps and autologous fat grafting procedures were favored across the literature, and regardless of the intervention of choice, patients reported satisfaction and improved life prospects. Conclusion The loss of facial fat is especially afflicting for patients as the bilateral lipoatrophy imparts an aged, cachexic look which negatively affects not only their self-image but their social status as well. Alternatives to approach lipoatrophy vary in their invasiveness, permanency, and feasibility; thus, treatments must be thoroughly tailored to each patient's needs and expectations. Barraquer Simons Syndrome is a rare subtype of lipodystrophy primarily affecting females, leading to fat loss in mainly the upper body. The negative social impact of the syndrome necessitates intervention, and patients receiving appropriate treatment reported improved psychosocial parameters. Treatment plans sh

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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