Basic research conducted on alloplant biomaterials.

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

To reduce antigenicity of allografts and stimulate their replacement by natural recipient tissues. Experimental allotransplantation of different tissues (fascias, tendons, derma, fat, etc.) with histological, histochemical, electron microscopical, electron histochemical examination 3, 5, 7, 14, 21, 30, 60, 120, 180 and 360 days postoperatively. Allografts of different tissues with glucosaminoglycans extracted from collagen fibers have low antigenicity and can be replaced by natural tissues. Allografts with these properties were named 'Alloplant'. Alloplant biomaterials can selectively stimulate natural tissue regeneration. Hence, Alloplant biomaterials can be utilized in surgery for the restoration of different tissues.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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