Bibliometric analysis of MXRA7 gene research trajectory: trends and insights (2015-2024)
Zhang H., Shen Y., Bai P., Wu X., Li P., Wang T.
Laboratory Study, published in Discov Oncol (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- Discov Oncol (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40459788
- PMCID
- PMC12134252
- DOI
- 10.1007/s12672-025-02824-5
Abstract (original English)
Background Matrix remodeling-associated 7 (MXRA7) plays a key role in physiological and pathological processes involving the extracellular matrix (ECM) and tissue remodeling. Recent studies have highlighted its functions in tissue injury, immune response, and cellular differentiation, yet no bibliometric studies have systematically mapped MXRA7 research. This study evaluates global MXRA7 research from 2015 to 2024 to identify current trends and future directions. Methods A comprehensive bibliometric analysis was conducted using the Web of Science Core Collection. We examined publication trends, geographical contributions, influential authors, and high-impact journals, identifying research hotspots and emerging trends with advanced bibliometric tools. Results Analysis of 553 English-language publications showed that MXRA7 research has progressed significantly after 2017, showing a general upward trend accompanied by short-term fluctuations. The United States leads, followed by China and the United Kingdom. Key studies appear in high-impact journals like PLOS ONE, and influential authors such as Frangogiannis NG have propelled the field. Keywords including "inflammation", "extracellular matrix", "matrix metalloproteinases" and "angiogenesis" underscore MXRA7's roles in immune responses, tissue repair, and fibrosis. Conclusion This analysis shows significant growth in MXRA7 resear
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
How we grade evidenceBrowse all related research
Filter the research library by this study's title keywords, author, or publication year.