Biomedical Applications of Gadolinium-Containing Biomaterials: Not Only MRI Contrast Agent
Pan X., Hu M., Wu L., Wei E., Zhu Q., Lv L.
Narrative Review, published in Adv Sci (Weinh) (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Adv Sci (Weinh) (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40279569
- PMCID
- PMC12120756
- DOI
- 10.1002/advs.202501722
- Citations
- 2
Abstract (original English)
The potential applications of rare earth elements (REEs) in biomedical fields have been intensively investigated. Numerous studies have shown that doping biomaterials with REEs can enhance their properties. Gadolinium (Gd) is a biocompatible REE that holds promise in biomedical applications. This review examines the use of Gd-doped biomaterials in osteogenic, antimicrobial, anticancer applications, and in bioimaging and bioprobes, as reported in the literature until December 2024. The included studies demonstrate that Gd-containing biomaterials promote osteogenesis, enhance antimicrobial properties, and perform well in anticancer applications and bioimaging. Taken together, they point to the considerable potential of Gd-doped biomaterials and thus to avenues for future research.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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