Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

Brown Fat-Derived Exosomes: Small Vesicles with Big Impact.

Chen Y., Pfeifer A.

Laboratory Study, published in Cell Metab (2017) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Cell Metab (2017)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
28380368
DOI
10.1016/j.cmet.2017.03.012

Abstract (original English)

Adipose tissue (AT) not only stores energy, but also secretes hormones and releases small vesicles known as exosomes. Thomou et al. (2017) now show that exosomes secreted by brown fat carry miRNAs that regulate the liver. Thus, AT exosomes might have therapeutic and diagnostic relevance for metabolic disorders.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose Tissue, BrownExosomesHumansLiverMetabolic DiseasesMicroRNAs

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