Clinical outcomes and feasibility of 3D-printed titanium alloy scaffolds combined with platelet-rich plasma injection in the treatment of long-segment femoral defects
Xu R., Li J., Tu H., Sun M., Zhang Z., Duan S.
Prospective Study, published in BMC Res Notes (2026) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- BMC Res Notes (2026)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 41572383
- PMCID
- PMC12911096
- DOI
- 10.1186/s13104-026-07676-y
Abstract (original English)
OBJECTIVE: This study aimed to investigate the clinical efficacy and feasibility of 3D-printed titanium alloy scaffolds combined with autologous platelet-rich plasma (PRP) injection in the treatment of long-segment femoral defects. RESULTS: The mean follow-up duration for all patients in this study was 12.63 ± 1.02 months. At the final follow-up, the Visual Analogue Scale (VAS) score was 2.13 ± 1.15, significantly lower than the preoperative score of 6.31 ± 1.74 (P < 0.001). The Lower Extremity Functional Scale (LEFS) score was 54.88 ± 6.01, significantly higher than the preoperative score of 33.81 ± 8.05 (P < 0.001). The Lane–Sandhu score was 7.19 ± 1.38, and the patient-reported satisfaction score was 8.88 ± 1.02. No severe complications were observed during the follow-up period.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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