Clinical and ultrasonographic evaluation of breast lipofilling after expander extrusion. Case report
Bogdan RG., Helgiu A., Cimpean AM., Crainiceanu ZP.
Case Report / Series, published in Med Pharm Rep (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Case Report / Series
- Journal
- Med Pharm Rep (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 39949915
- PMCID
- PMC11817588
- DOI
- 10.15386/mpr-2826
Abstract (original English)
Background Breast cancer treatment often involves mastectomy and adjuvant therapies such as radiotherapy, which can lead to complications in reconstructive procedures. Tissue expanders are commonly used for immediate breast reconstruction post-mastectomy, but radiation therapy increases the risk of complications like expander extrusion. Lipofilling has emerged as a promising technique to address tissue damage and improve reconstructive outcomes. This case illustrates the utility of ultrasonography in measuring fat thickness before and after the lipofilling procedure and calculating the resorption rate for managing complex post-radiation complications. Case description We report the case of a 38-year-old patient born and raised in Romania with a history of right breast cancer, who initially underwent mastectomy followed by immediate reconstruction with a subpectoral tissue expander. The patient subsequently received adjuvant radiotherapy, which led to the extrusion of the tissue expander and chronic pain with skin redness. Due to significant damage to the surrounding tissue and chest wall, lipofilling was employed as a reconstructive approach to enhance skin quality and support tissue regeneration. Fat grafting was performed in multiple sessions, with ultrasonographic evaluations conducted before and after each session to monitor volumetric changes in the reconstructed breast. F
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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