A Combination of Conventional Transconjunctival Lower Blepharoplasty and Percutaneous Nanofat Grafting in a Young Chinese Population With Eyelid Bags and Tear Trough Deformities.
Liu C., Wu Z., Tang L., Zhang Z., Li J., Sun X.
Retrospective Study with a reported sample of 183, published in J Cosmet Dermatol (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Retrospective Study
- Journal
- J Cosmet Dermatol (2025)
- Country
- England
- Reported sample size
- 183
- Source database
- PubMed
- PMID
- 39846209
- PMCID
- PMC11755396
- DOI
- 10.1111/jocd.70009
- Citations
- 1
Abstract (original English)
Objective A simple and minimally invasive combined procedure, including transconjunctival orbital fat removal and transcutaneous resected orbital fat injection, was performed based on the anatomical characteristics of the lower eyelids in our young Chinese patients. Our study aimed to investigate the efficacy and safety of this procedure in our study population. Methods In our retrospective study, a total of 183 consecutive patients underwent a combination of traditional transconjunctival blepharoplasty and nanofat grafting between February 2020 and June 2024. After transconjunctival septal fat removal, the resected orbital fat was processed into fat emulsion (nanofat) and then injected percutaneously into the depressed tear trough zone. Results The mean age of the 183 patients was 26.9 years old, and the average surgery time was 36.1 min. The mean volume of nanofat injected for bilateral lower eyelids in each patient was 1.1 mL. All the patients were followed for at least 6 months after surgery, and the subjective patient satisfaction was 96.6% (175/183) with fewer complications. In the objective assessment of the surgical outcomes according to the five anatomical elements of lower eyelids, orbital fat prolapse, tear trough depression and dark circles were all improved, orbicularis prominence was more evident, while skin elasticity did not vary significantly after operation. C
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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