Combined therapies in scar treatment-The role of autologous derived agents in scar remodeling: A series of cases.

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Comprehensive scar treatment usually requires a combination of several methods. The selection of methods should depend on the appearance and biology of the scar. The aim of this study was to determine the safety and efficiency of combined methods with the use of autologous derived agents in the treatment of scars, based on the available literature and own experience. The study consists of a description of three cases treated with autologous derived agents: platelet-rich plasma (PRP), lipofilling or stromal vascular fraction (SVF) in combination with radiofrequency, CO 2 laser, or cutting threads. No adverse events were reported. Improvement in scar quality and function was observed in all cases. Combination of autologous derived injectables with medical devices is safe and accelerates both cosmetic and functional results.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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