Level D· Scientific groundwork from lab and animal studiesLaboratory StudyEurope PMCOpen access

Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D / H Ratios in a Culture Medium

Zlatskiy IA., Zlatska AV., Antipova NV., Dolenko SA., Gordiienko IM., Gubar OS.

Laboratory Study, published in ScientificWorldJournal (2020) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
ScientificWorldJournal (2020)
Reported sample size
—
Source database
Europe PMC
PMID
32158363
PMCID
PMC7060866
DOI
10.1155/2020/2373021
Citations
5

Abstract (original English)

In this study, using new approach (laser diffraction + biological dyes), we have demonstrated the decrease of cells viability in vitro in the deuterated growth medium, whereas in the deuterium-depleted medium, there was an increase of cell viability. We have also found that not all dyes are equally sensitive to the D / H ratios in the culture medium (system) as well as to the different cell types (cancer vs normal cells).

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Cells, CulturedCell LineCell Line, TumorHumansDeuteriumCulture MediaCell Culture TechniquesLasersCell SurvivalMolecular Structure

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