Level C· Early human research exploring benefitsProspective StudyPubMed

Comparison Of Effects Of Stromal Vascular Fraction And Nano-Fat Applications On Skin Quality And Photoaging.

Buyukkaya O., Karakol P., Tapki MM., Bozkurt M.

Prospective Study with a reported sample of 10 on Skin Aging, published in Plast Reconstr Surg (2026) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
Plast Reconstr Surg (2026)
Country
United States
Reported sample size
10
Source database
PubMed
PMID
41811159
DOI
10.1097/PRS.0000000000013017

Abstract (original English)

Aim of this study is to evaluate the effectiveness of stromal vascular fraction (SVF) and nano-fat applications on photoaging and skin quality in the facial region, as well as their possible superiority over each other. Study was conducted on 20 volunteer patients aged 40-55 who applied to City Hospital Plastic Reconstructive and Aesthetic Surgery outpatient clinic between April-July 2024 with complaints of facial aging and skin complaints in facial area. After initial evaluation, patients were divided into two groups; SVF was injected into the facial region of 10 patients, and nano-fat was injected into facial region of the other 10 patients. Preoperative, postoperative 1st and 3rd month skin evaluations of the patients were made with the visa skin analysis system, and dermis thicknesses were measured with high-frequency ultrasound (HFU). The data obtained prospectively were statistically analyzed. In the visia skin evaluations of the patients, it was observed that SVF and nano-fat injection reduced wrinkle scores significantly (p<0.05). Also, SVF injection reduced ultraviolet (UV) damage, red area and porphyrin score significantly (p<0.05). No significant dermis change was detected in the dermis thickness measurement performed with HFU preoperatively and postoperatively. It was observed that SVF and nano-fat injections were effective on wrinkles and both applications were val

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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