Comparison of Surgical Techniques and Joint Injections for Base of Thumb Osteoarthritis: A Systematic Review

Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Purpose To perform an updated systematic review investigating the various surgical and injection interventions for thumb carpometacarpal (CMC) joint arthritis. Methods A systematic literature search was conducted in MEDLINE, Embase, Web of Science, and Cochrane databases from inception to April 2024 to identify prospective, randomized studies comparing surgical and/or minimally invasive interventions for thumb CMC joint osteoarthritis with a minimum follow-up of 12 months. Reference lists of previous reviews were screened to identify additional publications. Qualitative analysis was performed for primary and secondary outcomes based on the direction of effect (statistically higher, lower, or no difference) because of marked heterogeneity of data and inadequate statistical power. Cochrane's risk of bias 2 tool assessed the quality of included studies. Results Seventeen studies encompassing 1,166 thumbs were included in this review. Fourteen studies compared surgical interventions, whereas three studies compared various intra-articular injections. Five studies had a low risk of bias, eight had a moderate risk of bias, and four had a high risk of bias. Regarding primary outcomes, there was no difference in function between trapeziectomy and arthroplasty, key pinch strength between partial and total trapeziectomy, and pain and function between trapeziectomy and arthrodesis. Arthrod

Evidence level

Relatively higher-quality human studies compared with other topics in this database, e.g. multiple RCTs or systematic reviews. This does not mean it is standard or approved care.

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