Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

[Composite materials based on chitosan and montmorillonite: prospects for use as a matrix for stem and regenerative cell cultivation].

Popriadukhin PV., Dobrovol'skaia IP., Iudin VE., Ivan'kova EM., Smolianinov AB., Smirnova NV.

Laboratory Study, published in Tsitologiia (2011) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Tsitologiia (2011)
Country
Russia (Federation)
Reported sample size
—
Source database
PubMed
PMID
22359954

Abstract (original English)

This paper examines the structural and mechanical properties of composite materials based on chitosan and micro- and nanoparticles of Na-montmorillonite and possibility of application for cultivation and targeted delivery of mesenchymal stem cells and regenerative cells. It's have been shown by addition of Na-montmorillonite biomaterial acquires stability of structural and mechanical properties in the sterilization process the handling of liquid media in cell culture. In vitro studies using dermal fibroblasts and adipose tissue mesenchymal stem cells demonstrated that this material has a set of properties to ensure matrix biocompatibility.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueBentoniteCell Culture TechniquesCells, CulturedChitosanDermisFibroblastsHumansMesenchymal Stem CellsNanocomposites

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