SVF
Level D· Scientific groundwork from lab and animal studiesAnimal StudyPubMed

[Culture and pluripotentiality of human marrow mesenchymal stem cells].

Fu W., Lu Y., Piao Y.

Animal Study on Tendon Injury, published in Zhonghua Xue Ye Xue Za Zhi (2002) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Zhonghua Xue Ye Xue Za Zhi (2002)
Country
China
Reported sample size
—
Source database
PubMed
PMID
12133458

Abstract (original English)

To cultivate human mesenchymal stem cells (MSC) derived from fetal bone marrow and examine their pluripotentiality. Bone marrow mononuclear cells from human fetal femur were collected by Percoll gradient centrifugation. The low density cells including MSCs were cultivated and expanded in MSCGM media. The characteristics of the multipotent MSCs were observed by implanting them into nude mice for 4 weeks. Human fetal marrow MSCs were successfully cultivated and differentiated in vivo into many kinds of tissues such as bone, cartilage, adipose, skeletal muscle and tendon-like tissue. Human fetal marrow MSCs were multipotent stem cells.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AnimalsBone Marrow CellsCell Culture TechniquesCell DifferentiationCell DivisionCell TransplantationCells, CulturedHumansMesodermMice
Tendon Injury
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