Current applications and future perspectives on rare-earth-based materials in stomatology
Dong Z., Lu X., Zhang W., Tang S., Liu H., Zhang R.
Narrative Review, published in iScience (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- iScience (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40822902
- PMCID
- PMC12357100
- DOI
- 10.1016/j.isci.2025.113220
- Citations
- 2
Abstract (original English)
A confluence of factors, including the incompatibility of conventional materials with the oral environment, inadequate dynamic response, and insufficient multi-objective synergy, hinders precise diagnosis and efficient treatment in contemporary stomatology. Due to their unique electronic configuration and multivalent properties, rare earth elements (REEs) have shown excellent optical response, enzyme simulation activity, antibacterial efficacy, and biological regulation potential. These attributes offer a promising path for developing a new generation of oral functional materials. To align the unique properties of REEs and the clinical demands, this article summarizes the current knowledge of physicochemical properties and biological functions of REEs, and provides a comprehensive overview of the cutting-edge applications of rare-earth-based materials in oral medicine. We anticipate that this review will enhance the understanding of the interdisciplinary value of rare-earth-based materials in stomatology, thereby contributing to the improvement of future oral healthcare.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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