Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMC

Current and Emerging Biologic Therapies for Equine Tendon and Ligament Injuries

Connard SS., Schnabel LV.

Narrative Review on Tendon Injury, Ligament Injury, published in Vet Clin North Am Equine Pract (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Vet Clin North Am Equine Pract (2025)
Reported sample size
—
Source database
Europe PMC
PMID
40517032
PMCID
PMC13291840
DOI
10.1016/j.cveq.2025.04.008

Abstract (original English)

This review explores the use of biologics in the treatment of tendon and ligament injuries in horses, focusing on current and emerging therapies aimed at enhancing tissue repair and regeneration. It discusses the role of scaffold-based therapies, growth factors, blood-derived and tissue-derived biologics, and gene therapy as biologic regenerative therapies for improving healing outcomes. The review evaluates the mechanisms, efficacy, and challenges of biologics in clinical applications, highlighting recent advances and clinical studies. It provides an overview of current trends and future directions for biologic therapies in equine musculoskeletal injuries.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
LigamentsAnimalsHorsesTendon InjuriesHorse DiseasesBiological ProductsBiological TherapyGenetic Therapy

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