From Dry Cavities to Healing Pathways: Innovations in Managing Empty Nose Syndrome
Surbhi, Anand A., Sinha V.
Laboratory Study, published in Indian J Otolaryngol Head Neck Surg (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- Indian J Otolaryngol Head Neck Surg (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40837841
- PMCID
- PMC12361013
- DOI
- 10.1007/s12070-025-05445-0
Abstract (original English)
Background Empty nose syndrome remains one of the rare and least touched topics worldwide. It needs to be dealt with in detail to understand its cause, pathophysiology, types and treatment options that are available at present. Still today management plans related to pathogenesis have not yet reached common consensus. The primary objective of this review is to present and evaluate the newer treatment options and techniques of empty nose syndrome. Design Systematic literature review. Methods A comprehensive search was conducted across multiple databases, including PubMed, Embase, Cochrane CENTRAL, and Google Scholar, covering the period from 1970 to 2024 was performed for studies of recent and newer options available for treatment of empty nose syndrome All included articles were categorized according to level of evidence. Results Five hundred and sixty papers were identified, of which 18 were found to be relevant for this review. There are multiple techniques used in treatment of the same but still there is no consensus as to what the specific and best options are for the patient. Conclusions and recommendations Turbinate resection should be done judiciously and invasive nasal surgeries should be opted as a last resort or preferentially after medical treatment.We support the cautious use of these screening tools as adjuncts to clinical decision-making and early diagnosis. Post-
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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