Level C· Early human research exploring benefitsProspective StudyPubMed

Effect of age and body mass index on the yield of stromal vascular fraction.

Alaaeddine N., El Atat O., Saliba N., Feghali Z., Nasr M., Tarabey B.

Prospective Study with a reported sample of 58, published in J Cosmet Dermatol (2017) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
J Cosmet Dermatol (2017)
Country
England
Reported sample size
58
Source database
PubMed
PMID
29222844
DOI
10.1111/jocd.12458
Citations
16

Abstract (original English)

Objective The aim of this study was to determine the influence of age, body mass index, and site of liposuction on the cell yield of SVF. Methods A prospective study was performed on 58 patients. The average age was 39 years old, with BMI ≤ 25 or BMI ≥ 25. Fat tissue was harvested from the abdominal region, flanks, or thighs and SVF was isolated. Results The yield of viable SVF was evaluated by trypan blue, and the markers of stem cells were evaluated by flow cytometry. The cells were positive for stem cells markers, the age, sex of the patient had no impact on SVF cell yield with an average of 1.17 × 10^8. However, the BMI > 25 had resulted in higher cell numbers, and the harvest site had a significant impact on cell yield with abdomen being the site of interest. Conclusion These data demonstrate that the age of the person does not affect the cell yield of SVF; nevertheless, the donor site and BMI might be important factors in affecting cell number.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
AbdomenAdipose TissueAdultAge FactorsAgedBody Mass IndexFemaleHumansLipectomyMale

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