The effect of autologous adipose derived mesenchymal stem cell therapy on juvenile osteochondritis dissecans of the patella: a case study.
Russo A., Coco V., Zaffagnini S.
Case Report / Series, published in J Surg Case Rep (2020) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Case Report / Series
- Journal
- J Surg Case Rep (2020)
- Country
- England
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 32904720
- PMCID
- PMC7458149
- DOI
- 10.1093/jscr/rjaa274
- Citations
- 3
Abstract (original English)
A prospective analysis of the effect of autologous adipose derived mesenchymal stem cell (AD-MSCs) therapy in the treatment of a juvenile osteochondritis dissecans (JOCD) of the patella. After failed conventional management of JOCD, a 13-year-old patient undergoes intra-articular MSC therapy. Repeated magnetic resonance imaging analyses showed regeneration of cartilage. In this report, the use of AD-MSCs, after unsuccessful conventional JOCD management, resulted in structural, functional and pain improvement. These results highlight the possibility to avoid surgery treatment in JOCD patella treatment.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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