Level C· Early human research exploring benefitsRetrospective StudyPubMed

Effectiveness of Acupotomy Subcision and Nanofat Grafting in Depressed Scars Treatment.

Qu M., Zhang T., Sun M., Zhang S., Fu Q., Chen G.

Retrospective Study with a reported sample of 32 on Scar, published in Aesthetic Plast Surg (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Aesthetic Plast Surg (2025)
Country
United States
Reported sample size
32
Source database
PubMed
PMID
40588640
DOI
10.1007/s00266-025-04936-3

Abstract (original English)

Purpose The purpose of this study was to investigate the effectiveness of the combined treatment of acupotomy subcision and Nanofat grafting in depressed scars. Methods A single-center retrospective analysis was performed on 32 patients with moderate to severe depressed facial scars treated between November 2020 and April 2023. The treatment involved acupotomy subcutaneous scrape, followed by Nanofat injection. Clinical assessments included measurement of scar concavity using a 3D camera, the Patient Observer Scar Assessment Scale (POSAS), and a skin analysis system to evaluate collagen and elastin levels. Results The study found a significant reduction in scar concavity from a mean of -0.90 ± 0.44 mm pre-treatment to -0.10 ± 0.18mm six months post-treatment. POSAS scores showed substantial improvements in scar esthetics at 6 months post-operation. There was also a significant increase in skin elasticity and a decrease in skin collagen levels following treatment. Conclusion The combined application of acupotomy subcision and Nanofat grafting was effective in reducing the depression of depressed scars, leading to significant improvements in scar appearance and patient satisfaction. This approach offers a minimally invasive and effective treatment option for patients with depressed scars. Level of evidence v This journal requires that authors assign a level of evidence to each ar

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
HumansCicatrixFemaleRetrospective StudiesAdultMaleTreatment OutcomeMiddle AgedAcupuncture TherapyYoung Adult

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