Emerging treatments for chronic neuropathic pain from a cross-disease perspective: developments and applications of nanomaterials
Sun R., Zhang X., Dou T., Xiao Z., Deng X.
Narrative Review, published in J Headache Pain (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- J Headache Pain (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40528184
- PMCID
- PMC12172365
- DOI
- 10.1186/s10194-025-02081-5
- Citations
- 4
Abstract (original English)
Chronic neuropathic pain (CNP) results from disease or damage within the somatosensory nervous system. It represents a prevalent and challenging form of chronic pain that exerts a severe impact on patients' quality of life. This review aims to synthesize and highlight the current understanding of the mechanisms underlying CNP, as well as the evolving therapeutic landscape. With advancements in research, an increasing number of analgesic targets specific to various disease types are being developed, alongside the emergence of novel nanomaterials for treating chronic pain. In this review, we systematically summarize the applications and potential mechanisms of nanomaterials in treating CNP induced by various diseases, providing new insights for both fundamental research and clinical management of CNP.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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