The Evolution of Knifeless Microcolumn Fat Injection in 1362 Patients: Emphasizing Longevity of Results and Optimal Contour
Sullivan PK., Palmer SK., Gomez DA.
Prospective Study with a reported sample of 1362 on Scar, published in Plast Reconstr Surg Glob Open (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- Plast Reconstr Surg Glob Open (2025)
- Reported sample size
- 1362
- Source database
- Europe PMC
- PMID
- 40995578
- PMCID
- PMC12456580
- DOI
- 10.1097/gox.0000000000007118
Abstract (original English)
Background The field of regenerative surgery has been revolutionized by minimally invasive fat injection methods. Over the past decades, techniques have evolved significantly. However, concerns regarding long-term volume retention and creating the desired result remain a challenge for many surgeons. Methods Our experience with 1362 patients has led to the development of a refined microfat injection technique that achieves durable facial contouring with a single treatment. Our method eliminates the need for overinjection, reducing the risks of contour irregularities and unpredictable fat resorption. The technique is knife-free, minimizing scarring and improving patient satisfaction. Results Meticulous preoperative planning is paramount. Targeted areas are drawn on the face and delineated in subunits. These recipient sites undergo preinjection with a vasoconstrictive agent, mirroring the planned fat volume. This allows intraoperative assessment and precise volume refinement. Fat is harvested, processed, and injected in microcolumns using blunt side-port cannulas ranging from 17 to 20 G cannulas, with each pass depositing 0.025 to 0.05 mL in a new vascularized plane. This systematic microcolumnar deposition of small threads of fat ensures uniform augmentation, optimal vascularization, and long-term volume preservation. Conclusions This technique is particularly advantageous to del
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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