Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

Fabrication of novel 3D nanofiber scaffolds with anisotropic property and regular pores and their potential applications.

Xie J., Ma B., Michael PL.

Laboratory Study, published in Adv Healthc Mater (2012) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Adv Healthc Mater (2012)
Country
Germany
Reported sample size
—
Source database
PubMed
PMID
23184805
DOI
10.1002/adhm.201200100
Citations
14

Abstract (original English)

A new and simple approach for preparing 3D nanofiber scaffolds in a basket-weaved structure composed of uniaxially aligned, electrospun nanofiber strips is reported. It is also demonstrated that human adipose-derived stem cells seeded are distributed uniformly throughout different layers of scaffolds and can proliferate and be organized by the nanotopographic cues imparted by uniaxial arrays of nanofiber.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AnisotropyBiocompatible MaterialsElectrochemistryEquipment DesignEquipment Failure AnalysisHumansPorosityTissue Scaffolds

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