Level C· Early human research exploring benefitsCase Report / SeriesPubMed

Fat Graft Transfer in Nasal Tip Reconstruction.

Raponi I., Pallini V., Valentini V., Giovannetti F., Marzetti A.

Case Report / Series with a reported sample of 9 on Face & Skin, published in J Maxillofac Oral Surg (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Case Report / Series
Journal
J Maxillofac Oral Surg (2025)
Country
India
Reported sample size
9
Source database
PubMed
PMID
42528896
DOI
10.1007/s12663-025-02710-1

Abstract (original English)

To assess the esthetic and functional outcomes of reconstructing small cutaneous nasal tip defects with fat graft transfer. Under local anesthesia, fat graft transfer was performed in nine patients affected by non-melanoma skin cancer of the nasal tip to fill surgical gap. A NAFEQ questionnaire was submitted to all patients to verify nasal function and appearance. The surgery was uneventful in all cases. In most of the patients (8 of 9 patients), the adipose tissue graft remained vital and re-epithelization started from the edges of the resected area. In three patients, a hematoma in the donor site was observed. All patients were satisfied of esthetical appearance of the nasal tip and of the nasal function. The fat tissue graft is a good reconstruction option because it gives both good esthetic and functional results, and it can be performed also in elderly patients with many comorbidities. The online version contains supplementary material available at 10.1007/s12663-025-02710-1.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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