Level C· Early human research exploring benefitsProspective StudyEurope PMCOpen access

Fat Grafting following Internal Tissue Expansion: An Option for Breast Reconstruction after Total Mastectomy

Kolasinski J., Pyka P.

Prospective Study with a reported sample of 11, published in Plast Reconstr Surg Glob Open (2022) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
Plast Reconstr Surg Glob Open (2022)
Reported sample size
11
Source database
Europe PMC
PMID
35169521
PMCID
PMC8835577
DOI
10.1097/gox.0000000000004088
Citations
6

Abstract (original English)

Background Breast reconstruction is currently performed as standard practice. Methods A prospective study was performed of patients after total mastectomy who underwent autologous breast reconstruction with fat grafting (FG) combined with internal tissue expansion between September 2015 and December 2020. The patients were classified into groups A to F depending on the steps of breast reconstruction. Groups A and B described patients with completed breast reconstruction with FG and expander removal, with or without nipple/areola complex reconstruction. C described patients during deflation of the expander combined with simultaneous FG. D described patients after expander implantation and refilling. E described patients after first FG, and F included patients who discontinued reconstruction with the described method and converted to reconstruction with a breast implant. Results Among 22 treated patients' two were after first FG (9.09%' group E), two were after expander implantation and refilling (9.09%' group D), three were during deflation of the expander combined with simultaneous FG (13.63%' group C), and four (18.18%) had completed breast reconstruction-two (9.09%) without NAC reconstruction and symmetrization (group B) and two (9.09%) with completed breast reconstruction (group A). In 11 patients (50%), breast reconstruction was abandoned after expander implantation and one

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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