Level D· Scientific groundwork from lab and animal studiesNarrative ReviewPubMed

Fatty acids and adipose cell differentiation.

Ailhaud G., Amri EZ., Grimaldi PA.

Narrative Review, published in Prostaglandins Leukot Essent Fatty Acids (1995) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Prostaglandins Leukot Essent Fatty Acids (1995)
Country
Scotland
Reported sample size
—
Source database
PubMed
PMID
7784445
DOI
10.1016/0952-3278(95)90008-x

Abstract (original English)

Fatty acids are important metabolic substrates for adipose tissue. In preadipose cells, fatty acids are also potent inducers of various genes encoding proteins directly involved in fatty acid metabolism. On a longer-term basis, fatty acids induce the terminal differentiation of preadipose to adipose cells. Fatty acids act primarily at a transcriptional level. A member of the steroid/thyroid hormone receptor superfamily has been identified by cDNA cloning from a mouse Ob1771 preadipose cell library. This receptor is likely the fatty acid-activated receptor implicated in the transcriptional effects of fatty acids in adipose cells. Thus fatty acids appear to play a new role as signal transducing molecules which are involved in adipose cell differentiation.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AdipocytesAnimalsCell DifferentiationCell DivisionCell LineFatty AcidsGene Expression RegulationGene LibraryMiceReceptors, Cytoplasmic and Nuclear

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