Frontal sinus obliteration: a comparison of fat, muscle, bone, and spontaneous osteoneogenesis in the cat model.
Mickel TJ., Rohrich RJ., Robinson JB.
Animal Study, published in Plast Reconstr Surg (1995) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Animal Study
- Journal
- Plast Reconstr Surg (1995)
- Country
- United States
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 7870789
Abstract (original English)
The obliteration of the frontal sinus is frequently necessary in the appropriate treatment of trauma, chronic infection, and benign tumors, but the various methods have not been directly compared previously. This study compares four treatment groups (seven cats per group) specifically of implantation of autologous fat, muscle, and bone and spontaneous osteogenesis done using a strictly standardized operative technique in an unfractured, uninfected feline frontal sinus model. All methods studied were effective in sinus obliteration; however, significant morbidities occurred at the donor sites when autologous tissue transplantation was used. Therefore, spontaneous osteogenesis appears to be the method of choice for frontal sinus obliteration.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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