Level D· Scientific groundwork from lab and animal studiesNarrative ReviewPubMed

Frontal sinus obliteration: in search of the ideal autogenous material.

Rohrich RJ., Mickel TJ.

Narrative Review, published in Plast Reconstr Surg (1995) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Plast Reconstr Surg (1995)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
7870788

Abstract (original English)

The controversies concerning obliteration of the frontal sinus in response to trauma, infection, or tumor growth are long-standing (1913 to the present) and related to the field of training of the surgeon. Successful frontal sinus obliteration requires (1) meticulous removal of the frontal sinus mucosa, (2) removal of the inner cortex of the sinus wall, and (3) permanent occlusion of the nasofrontal duct. It is significant to note that most of the clinical literature relates to management of infected sinuses (sinusitis) and most experimental studies are done on uninfected, unfractured feline models. Therefore, no direct reference can be made to the management of the fractured frontal sinus. The techniques in current use are autologous implantation of fat, bone, and muscle, along with the technique of spontaneous osteogenesis. These techniques are all effective when the preceding guidelines are followed, with the only real advantage being that the spontaneous osteogenesis avoids the problem of donor-site morbidity, which has been as high as 5 percent. This factor makes the osteogenesis technique the method of choice for frontal sinus obliteration. This literature review provides the surgeon with the objective data available for optimal frontal sinus obliteration.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueAnimalsBone TransplantationFrontal SinusHumansMucous MembraneMusclesOsteogenesisParanasal Sinus DiseasesProstheses and Implants

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