Level D· Scientific groundwork from lab and animal studiesAnimal StudyPubMedOpen access

Generation of Functional Human Adipose Tissue in Mice from Primed Progenitor Cells.

Rojas-Rodriguez R., Lujan-Hernandez J., Min SY., DeSouza T., Teebagy P., Desai A.

Animal Study, published in Tissue Eng Part A (2019) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Tissue Eng Part A (2019)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
30306830
PMCID
PMC6590775
DOI
10.1089/ten.TEA.2018.0067
Citations
20

Abstract (original English)

Impact statement This research describes the use of human mesenchymal progenitor cells for generating functional adipose tissue in vivo in a nude mouse model. Further preclinical development of the methods and insights described in this article can lead to therapeutic use of these cells in regenerative and reconstructive medicine.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AdipocytesAdipose TissueAnimalsCell DifferentiationHeterograftsHumansMaleMesenchymal Stem Cell TransplantationMesenchymal Stem CellsMice

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