Gibberellic Acid (GA 3 ): A Versatile Chiral Building Block for Syntheses of Pharmaceutical Agents
Alabdeen Khdar Z., Le TM., Szakonyi Z.
Narrative Review, published in Chem Biodivers (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Chem Biodivers (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 39307688
- PMCID
- PMC11741152
- DOI
- 10.1002/cbdv.202401823
- Citations
- 3
Abstract (original English)
Gibberellic acid (GA 3 ), an ent-kaurene tetracyclic diterpene, has been considered to be a chiral pool for the chemical transformation of significant heterocyclic compounds. This chiral pool continues to influence modern synthetic chemistry as an inexpensive and versatile starting material since it is widely applied in agriculture. This review focuses on the stereoselective syntheses of bioactive agents with pharmaceutical potency prepared from Gibberellic acid.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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