Global research trends of platelet-rich plasma (PRP) in orthopedic sports injuries: A bibliometric analysis from 2000 to 2024

Several human studies show positive signals, while research methods and sample sizes continue to develop.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Background A bibliometric and knowledge-map analysis is used to explore platelet-rich plasma (PRP) applications in orthopedic sports injuries. It aimed to summarize global research trends related to clinical trials and provide new insights for researchers in this field. Methods The articles and reviews regarding PRP applications in sports injuries were retrieved from the Web of Science Core Collection (2000-2024). CiteSpace, VOSviewer, HistCite Pro, R-Studio, and other analytical tools were used to conduct the bibliometric analysis and visualization of trends, collaborations, and emerging topics. Results Ten thousand eight hundred thirty-five authors from 3231 institutions published 2601 papers in 802 academic journals in 105 scientific categories. The United States was absolutely in the leading position in this research field. The institution that contributed the most publications was the Harvard University. Nicola Maffulli published the most articles and had the most co-citations. Extensive nodes and links indicate close scientific collaboration among countries, institutions, and authors. The most influential research focused on the fundamental aspects of PRP, particularly its application in regenerative medicine as a nonsurgical intervention for sports injury repair. Diverse sports injury models have been employed to investigate the efficacy of PRP. The latest hotspots and t

Evidence level

Several human studies show positive signals, while research methods and sample sizes continue to develop.

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