High-Density Fat Combined With Stromal Vascular Fraction Gel for the Treatment of Facial Localized Scleroderma.

Early human evidence such as case series or small samples is exploring possible benefits.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Patients with localized scleroderma on the face typically exhibit asymmetrical linear or patchy skin lesions and indentations on areas such as the scalp and forehead, with a smooth, waxy surface. In the early stages, medication is used to control the progression of the disease. In later stages, plastic surgery is performed to repair facial skin lesions. The authors treated 2 patients with localized scleroderma of the face using high-density fat combined with stromal vascular fraction gel transplantation surgery. The patients were satisfied with the color and texture of their skin, as it closely resembled the surrounding normal skin. In addition, the facial indentations were corrected, restoring a normal appearance to the face. This method is aesthetically pleasing, durable, and safe.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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