Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

[Historical review of the use of adipose tissue transfer in plastic and reconstructive surgery].

Mojallal A., Foyatier JL.

Laboratory Study, published in Ann Chir Plast Esthet (2004) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Ann Chir Plast Esthet (2004)
Country
France
Reported sample size
—
Source database
PubMed
PMID
15518942
DOI
10.1016/j.anplas.2004.08.004

Abstract (original English)

Use of adipose tissue transfer in plastic and reconstructive surgery is not new, and has been the subject of numerous studies. Transfer of autologous adipose tissue was reported for the first time at the end of the 19th century. Ideas and techniques have greatly changed during the last century. Adipocyte transfer has attracted renewed interest in recent years, due in particular to the development of Lipostructure by Coleman, who introduced a procedure based on strict methodology and the use of specific material. The history of adipose tissue transfer is retraced through the works of various authors and briefly recounted by highlighting the major landmarks of its advance. The evolution of ideas and techniques can be divided into three periods. The period before the introduction of lipoaspiration was termed "open surgery", when adipose tissue was harvested by surgical excision. The next period is that following the discovery of lipoaspiration, called the "unrefined" period, during which adipose tissue was obtained by aspiration and reinjected without preparation. During the third period, following the works of Coleman, the adipose tissue now undergoes non-traumatic refinement before grafting; this period is called "non-traumatic refined". Various studies have shown that this technique causes little damage to the cells and have demonstrated survival of the tissue transferred. Disc

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AdipocytesAdipose TissueCell SurvivalHistory, 19th CenturyHistory, 20th CenturyHumansPlastic Surgery ProceduresSurgery, PlasticTransplantation, Autologous

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